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KMID : 0363220110490020198
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Korean Journal of Dermatology
2011 Volume.49 No. 2 p.198 ~ p.201
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Overlap Syndrome with Features of Actue and Chronic Cutaneous Graft-versus-host Disease
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Cheon Min-Suk
Lee Young-Bok
Kim Jung-Eun
Cho Baik-Kee
Park Hyun-Jeong
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Abstract
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Graft-versus-host disease (GVHD) has been divided into acute GVHD and chronic GVHD on the basis of 100 days post-transplantation. Recently, the National Institutes of Health in the USA proposed new consensus criteria for chronic GVHD; 1) classic chronic GVHD, presenting with diagnostic features of only chronic GVHD without characteristics of acute GVHD and 2) an overlap syndrome in which there are distinctive manifestations of chronic GVHD together with features of acute GVHD, irrespective of the period after transplantation. Herein we report a case of overlap syndrome that developed in a 15 year-old male who had undergone unrelated peripheral blood stem cell transplantation 4 years earlier.
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KEYWORD
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Graft-versus-host disease, Overlap syndrome, Stem cell transplantation
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